Mesenchymal stromal cells biology and clinical applications editors hematti peiman covers of the biology of mscs latest understanding of mechanisms of action and role in tissue homeostasis and regeneration identifies the potential of mscs in proceeding from bench to bedside from regulatory gmp production ethical and safety aspects critical analysis of clinical studies and the . Notify me of updates to mesenchymal stromal cells mscs biology mechanisms of action and clinical uses tell a friend tell someone you know about this product. The past decade has seen an explosion of research directed toward better understanding of the mechanisms of mesenchymal stem stromal cell msc function during rescue and repair of injured organs and tissues in addition to delineating cell cell signaling and molecular controls for msc differentiation the field has made particular progress in defining several other mechanisms through which . In addition to their stem progenitor properties mesenchymal stromal cells mscs possess broad immunoregulatory properties that are being investigated for potential clinical application in treating immune based disorders. Mesenchymal stromal cells mscs have been the subject of clinical trials for more than a generation and the outcomes of advanced clinical trials have fallen short of expectations raised by encouraging pre clinical animal data in a wide array of disease models
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